Report #10
ZEOLITE
Zeolite clinoptilolite
Micronized Zeolite (MZ)


A new natural substance became recently available, with powerful cancer fighting and chelating capabilities. It is called Zeolite. Although it has only been developed a few years ago, it has already been incorporated into important cancer protocols, and there are a number of companies that are marketing it on the internet. It is not a drug, no prescription is needed, and it is entirely non-toxic. Below is one of the product descriptions. (The type of zeolite used in liquid zeolite is scientifically called clinoptilolite, a name often used in research papers.)

From http://www.drzeolitedetox.com/prevention.html


Zeolites are natural volcanic minerals that are mined in certain parts of the world. When volcanoes erupt, molten lava and thick ash pour out. Because many volcanoes are located on an island or near an ocean, this lava and ash often flows into the sea. Thanks to a chemical reaction between the ash from the volcano and the salt from the sea, amazing minerals like zeolites are formed in the hardened lava over the course of thousands of years.

What makes zeolite so amazing is the fact that it's not only one of the few negatively-charged minerals found in nature, but it also has a very unique structure. Zeolites have large, vacant spaces—or cages—that allow space for large, positively charged ions to be attracted to it, then trapped and eliminated from the body.

The class of minerals known as zeolites was first discovered in 1756 by Swedish mineralogist Axel Fredrick Cronstedt. Specifically, he discovered stilbite, one type of zeolite. He found that stilbite visibly lost water when heated. Based on this anomaly, he named the class of materials zeolites — Greek for "boiling stones."

For nearly 200 years, zeolites were considered an obscure little group of minerals—until we learned that its unique complex, crystalline framework of cavities and channels has many useful purposes—including detoxification.

More recently, the medical community has been looking into the cancer-fighting potential of zeolites and very much liking what they saw. Zeolites are minerals found in nature; they are 100 percent natural, safe and non-toxic. Specific forms of zeolites have also been recognized by the Federal Drug Administration (FDA) with GRAS status, which means generally recognized as safe. Zeolites have been shown to trap heavy metals—like mercury, lead, cadmium and arsenic—in its 'cages' and safely remove them from your system through the body's waste process.

According to 2003 issue of Anticancer Research, micronized zeolite, combined with a standard chemotherapy treatment (Doxorubicin), reduced the metabolic rate of cancer cells, significantly reduced the amount of metastasis to the lungs and increased the anti-cancer effects of the chemotherapy treatment.

Similarly, a Ph.D. researcher working for a small pharmaceutical company in Ohio found that micronized zeolites provide amazing results for treating cancer. After researching and testing zeolite's ability to treat epithelial cell cancer (the skin tissues that cover and line your body and all of your bodily organs), he was granted an exclusive patent by the U.S. government, entitled "Epithelial Cell Cancer Drug." His research showed that zeolites, when injected directly into a cancerous tumor, had a 100 percent kill rate.

What are epithelial cells?
Epithelial cells are skin tissues that cover and line the body. They cover all the body's organs (throat, lung, heart, breast, prostate, kidneys, liver, ovaries and colon) and line the body's cavities (including the inside of the chest and abdominal cavity). Cancers of the epithelial cells are called "carcinomas" and make up about 85 percent of all cancers.

In a scientific abstract it is stated:

Clinoptilolite treatment of
mice and dogs suffering from a variety of tumor types led
to improvement in the overall health status, prolongation
of life-span, and decrease in tumors size. Local application
of clinoptilolite to skin cancers of dogs effectively
reduced tumor formation and growth. In addition, toxicology
studies on mice and rats demonstrated that the
treatment does not have negative effects. In vitro tissue
culture studies showed that finely ground clinoptilolite
inhibits protein kinase B (c-Akt), induces expression of
p21WAF1/CIP1 and p27KIP1 tumor suppressor proteins, and
blocks cell growth in several cancer cell lines.
From: Natural zeolite clinoptilolite: new adjuvant in anticancer therapy
http://www.drzeolitedetox.com/Documents/zeolite-anticancer.pdf


Zeolite clinoptilolite has been on the FDA Generally Regarded As Safe (GRAS) list for forty years, literally hundreds of clinical studies have been performed noting it's non-toxic properties.

The substance has been patented as an anti-cancer agent. To read the US patent, please go to http://user156418.websitewizard.com/files/unprotected/productNCDPatent.pdf

Zeolite reduces cancer risk. From http://www.newstarget.com/015232.html

Finely ground natural zeolite powder has also been shown to induce activation of p21WAF1/CIP1. As a universal inhibitor of cyclin-dependent kinases and one of the target genes of the tumor suppresser p53, p21WAF1/CIP1 can act as a tumor suppresser through its ability to control cell cycle progression. Activation of p21WAF1/CIP1 may halt the growth of tumors by directly suppressing growth signals. However, tissue culture experiments demonstrated that activated zeolite particles inhibit protein kinase B/akt, another kinase involved in antiapoptotic processes and cancer promotion. This happens only when growth of cells in tissue cultures is stimulated by the addition of growth factors. Zeolite particles might adsorb growth factors or prevent interaction of protein kinase B with membranes, where it is phosphorylated by phosphatidylinositol 3-kinase. It has recently been shown that inactivation of protein kinase B by, for example, the novel tumor suppressor molecule PTEN also results in induction of the tumor suppressor-CDK inhibitor p27KIP1.

Dr. Gabriel Cousens on zeolite and cancer (http://www.newstarget.com/015232.html)

In a recently completed preliminary 14 month study, with 65 level four, terminal-stage cancer patients, sent home to die, 51 of the patients, or 78%, experienced complete remissions, (which means complete disappearance of the cancer). It appears to be effective for all forms of cancer, leukemias, and lymphomas.

When the zeolite moves inside the cell, the P21 gene is activated. P21 acts as a tumor suppressor through its ability to control cell cycle progression. The activation of P21 appears to halt the growth of tumors by directly suppressing growth signals. In in-vitro studies, all cancer cells tested were destroyed in 72 hours, which is a claim no other substance has been able to make. The beauty of it, of course, is that there are no side effects because it specifically targets cancer cells.

My primary interest is in cancer prevention, and preparing mothers for a healthy pregnancy. We do not want to ignore the fact of a preliminary study that shows approximately 78% of the terminally diagnosed people with cancer are now in remission. We have to say that zeolite is still in preliminary research. We cannot claim that this is a cure for cancer, but we can certainly look at it as a potent cancer prevention remedy.

Some PubMed abstracts on zeolite's anticancer properties:

Clinoptilolite is a nontoxic natural zeolite with properties of an ion-exchanger and adsorbent. Earlier studies showed that clinoptilolite could be an adjuvant in cancer therapy. The aim of this study was to define effects of clinoptilolite in cell media on cell viability and activity of key proteins regulating cell survival, cell division and stress response. The number of viable cells, DNA synthesis and activity of EGF-R, PKB/Akt and NF?B was reduced, while apoptosis was increased in cells that were cultured in medium supplemneted with clinoptilolite. (Abstract)

Anticancer and antioxidative effects of micronized zeolite clinoptilolite. (Abstract)

Micronized zeolite (MZ) administered by gastric intubation to mice injected with melanoma cells significantly reduced the number of melanoma metastases. In mice fed MZ for 28 days, concentration of lipid-bound sialic acid (LSA) in serum increased, but lipid peroxidation in liver decreased. The lymphocytes from lymph nodes of these mice provoked a significantly higher alogeneic graft-versus-host (GVH) reaction than cells of control mice. After i.p. application of MZ
(Micronized Zeolite), the number of peritoneal macrophages, as well as their production of superoxide anion, increased. However, NO generation was totally abolished. At the same time, translocation of p65 (NFkappaB subunit) to the nucleus of splenic cells was observed. CONCLUSION: Here we report antimetastatic and immunostimulatory effect of MZ and we propose a possible mechanism of its action. (Abstract)

Safety study proves absence of carcinogenity of clinoptilolite

The long term carcinogenicity of clinoptilolite was examined in Wistar rats. Respirable clinoptilolite was given intratracheally in doses 0, 30, or 60 mg/animal to groups of 60 or 50 male and 50 female rats on one occasion. No significant dose-related increase was found in the incidence of tumours in any organ or tissue. The results indicated that clinoptilolite type zeolite had no carcinogenic activity in Wistar rats. (Abstract)

We report a novel use of finely ground clinoptilolite as a potential adjuvant in anticancer therapy. Clinoptilolite treatment of mice and dogs suffering from a variety of tumor types led to improvement in the overall health status, prolongation of life-span, and decrease in tumors size. Local application of clinoptilolite to skin cancers of dogs effectively reduced tumor formation and growth. In addition, toxicology studies on mice and rats demonstrated that the treatment does not have negative effects. In vitro tissue culture studies showed that finely ground clinoptilolite inhibits protein kinase B (c-Akt), induces expression of p21WAF1/CIP1 and p27KIP1 tumor suppressor proteins, and blocks cell growth in several cancer cell lines. These data indicate that clinoptilolite treatment might adversely affect cancer growth by attenuating survival signals and inducing tumor suppressor genes in treated cells. (Abstract)

A reduced binding of 3H-8-OH-DPAT to 5-HT(1A) receptors in mammary carcinoma bearing mice was found when compared to control mice fed with standard food for 28 days, suggesting a time dependent alteration of 5-HT(1A) receptors in mammary carcinoma. The addition of MZ for 28 days in these mice abolished the decrease in 5-HT(1A) receptors binding, indicating a possible beneficial effect of MZ, at least on 5-HT(1A) receptors in mammary carcinoma bearing mice. (Abstract)

From http://www.cancerfightingstrategies.com/zeolite.html

Use Zeolite To Kill Cancer Cells... Without Harming Your Body
Zeolite is a remarkable volcanic mineral that has proven to be highly effective at destroying cancer cells. In fact, results have been so impressive, anyone fighting cancer or wishing to prevent cancer should be using zeolite. It comes in two forms....

Cellular Zeolite, a liquid zeolite, and Zeolite, a powdered micronized zeolite. They work on a couple of the basic issues in cancer. They are powerful detoxifiers and improve the alkalinity of your body. We list them as a cancer killer because of their ability to activate the P21 gene which tells a cancer cell to die, and because they can literally destroy the nucleus of cancerous cells.

Zeolite is a negatively charged volcanic mineral that naturally attracts positively charged toxins to it, and traps them in its cage-like structure. When zeolite is dug out of the ground, it will often have heavy metals bound up with it because it has an affinity to heavy metals. In making Cellular Zeolite, the zeolite is heated and cooled in a four day process to purify it of all toxins, and to give it a small amount of calcium, potassium and magnesium for ionic exchange.

In addition, Cellular Zeolite's heating and cleaning process makes a smaller molecular size zeolite that enables it to better travel throughout the body. Studies show that when you take measured quantity of Cellular Zeolite, 40% shows up in the stools -- meaning it works in the intestinal tract -- and 60% is found in the urine, meaning it gets into the bloodstream and works on cancer throughout the body.

Zeolite activates the p21 gene. The function of the p21 gene is to tell the cancer cell to die. P21 acts as a tumor suppressor as it controls cell cycle progression. The activation of P21 appears to halt the growth of tumors by directly suppressing growth signals. In in-vitro studies, all cancer cells tested were destroyed in 72 hour. There are no side effects because it specifically targets cancer cells as it is not attracted to normal healthy cells.

According to the patent, once it is pulled inside the cell, the tri metallic part of the zeolite molecule can destroy the nucleus and cytoplasmic organelles. In some cases the cancer cells were destroyed in an outward burst of the cytoplasm by increased osmotic pressure. In other cases cells were totally destroyed by cell wall and membrane collapse after the nucleus is destroyed. Most often, after the nucleus and the cytoplasm are destroyed, the entire cellular contents dissipate into the surrounding environment. The membrane of these now dead cancer cells remain intact, but no cellular structures are left.

The research shows that Cellular Zeolite works on the receptor sites, cell wall membrane proteins, and surface chemistry of the cancer cell only. It does not effect ordinary, healthy cells.

Zeolite fights cancer in other ways. It chelates and removes heavy metals, pesticides, herbicides, and other toxins from your body. It does this in a hierarchical manner. It is most attracted to lead, mercury, cadmium, arsenic and other heavy metals. Then chelates out pesticides, herbicides, plastics, and so forth. It also acts as a natural trap of viral particles which stops production of the viruses.

Because it traps toxins in its molecular structure, it detoxifies without overloading the detoxification system in your body. Because toxins are an underlying cause of almost all cancers, taking zeolite on a regular basis is an excellent cancer preventative. Especially as it can kill any cancer cells that may develop.

Is zeolite safe?

This particular form of zeolite used in both the liquid and powdered version, clinoptilolite, has been labeled 100% safe and non-toxic by the FDA. Just like with mushrooms, many types of zeolite are harmful, some aren't. There are more than 100 different zeolites. As an example, asbestos is a zeolite and causes cancer when inhaled as a fine powder. The zeolites we are talking about have been proven to be safe. They are a naturally-occurring non-fibrous clinoptilolite zeolite and is considered to be extremely safe and entirely non-toxic (even when inhaled).

This type of zeolite has been used in water filtration, air purification, plant fertilizers and animal feed for more than thirty years in the United States. Hundreds of published studies and articles outline its uses and benefits in humans and animals. A Med line search for "clinoptilolite" has no fewer than 140 articles on the uses of zeolite: removing heavy metals, improving the health of animals, treating viral disorders, removing fungal toxins, remediation of soil and treating cancer. In fact, there has been extensive testing done on this type of zeolite for use as an anti-diarrhea drug for humans.

What other medical professionals are saying.

"Tests strong in every case. A first step in even the most compromised situations. We’ve
seen results where none are expected, and recommend the Patented Liquid Zeolite highly to
all of our Doctors and patients."

- Dr. Dan Gleeson DC, DIBAK.

"This product provides a simple, natural, and highly effective way to detoxify the body. I
have seen phenomenal broad spectrum results in my practice in the first few weeks of
providing this product to my patients."  

- Dr. Tom Zorich DC, Rocklin, CA


PubMed Central White Paper
From European Biology Organization
(http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1326387)

Zeolites are naturally occurring or synthetic crystalline aluminosilicates. The pore network of a typical zeolite, which is confined by the framework, consists of cavities and connecting windows of uniform size As a result of these unique properties, zeolites can absorb gas and water molecules, facilitate ion exchange and act as 'molecular sieves' with long-term chemical and biological stability. Zeolites have therefore already become interesting subjects in different areas of chemical research and are now widely used in industrial, agricultural, environmental and biological technology (Mumpton, 1999). There are obvious structural similarities between the cages of zeolites and the substrate-binding sites of enzymes, which have led to the development of zeolite structures that mimic enzyme functions. Another approach would be to incorporate key features of selected enzymes, such as metal complexes, in zeolites—so-called 'ship-in-a-bottle' complexes—that could be used as oxygen carriers, mimicking haemoglobin, cytochrome P450 and iron–sulphur proteins (Bedioui, 1995).

Several toxicological studies of a natural zeolite named clinoptilolite proved that this compound is non-toxic and safe for use in human and veterinary medicine. Recent experiments in vitro and in vivo have suggested that clinoptilolite could be used as an adjuvant in anticancer therapy (Pavelic et al., 2001). So far, zeolites have been successfully used as detoxicants and decontaminants—when added to animal diets they reduce the level of heavy metals and organopoisoning, radionuclides and ammonia—as well as antibacterial and antidiarrhoeal agents. Zeolites have been used for haemodialysis, and also in cartridges in haemoperfusions. Zeolite powder has been shown to be effective in the treatment of athlete's foot and in reducing the healing time of wounds and surgical incisions. Tissue conditioners containing silver-exchanging zeolites showed a strong antimicrobial effect. On the basis of these findings and positive double-blind clinical studies, the drug Zeomic (Sinamen-Zeomic, Nagoya, Japan) was recently approved in Japan as an antimicrobial agent for dental treatments (Pavelic & Hadzija, 2003).

From the Brewer Science Library, New Horizons Newsletter:
http://www.mwt.net/~drbrewer/zeolite.htm
Zeolite: Powerful New Supplement from Volcanic Rock

The Ruder Boskovic Institute in Croatia was instrumental in carrying out the initial pre-clinical testing of zeolite. The zeolite used for medical purposes was processed by a special micronization machine (TMAZ) that increased the surface area several times over, and ground the material into various sized particles, with about 15% being nano-particles (as small as 100 nm).

After many months of testing for any toxic effect on mice and rats, no toxic effects were found.

Many other research studies in Croatia, Austria and Germany have reported positive effects on many different health conditions.

The researchers found the zeolite given in capsule form to be beneficial for various types of cancer, some viral infections, Crohn's disease, early MS patients, and some other neurological diseases.

Researchers worked at determining exactly how the micronized zeolite with its high proportion of nano-particles, affected the progress of these various diseases, especially cancer.

Besides shifting the body toward an alkaline state, reducing the high acid environment around cancer cells, increasing the antioxidant activity, reducing free radicals, research studies also revealed that in tissue cultures it demonstrated anti-cancer activity by induction of expression of p21WAF1/CIP1 and p27KIP1 tumor suppressor proteins, as well as inhibition of protein kinase B (c-Akt).

The results listed below with both canine and human cancers, were with micronized zeolite (TMAZ) combined with calcium and magnesium in a patented formula called Megamin.


TREATING CANINE CANCER:

Dr. Ljiljana Bedric, Ph.D., at the Faculty of Veterinary Medicine in Zagreb, Croatia, led the research treatment of 51 dogs with various cancers.

All dogs improved with oral zeolite treatment. Some dogs had dramatic reduction or elimination of their cancerous tumors.

One week of treatment for six dogs with prostate cancer resulted in resolution of their symptoms. Eight dogs with lymphoma also responded quickly. Ten dogs with mucous membrane tumors or skin tumors responded positively during oral treatment, but regressed again when the zeolite was withdrawn, and when treatment resumed, the tumors again decreased. Ten female dogs with mammary gland tumors demonstrated a 50% reduction in large tumors within three to four weeks, with their small tumors being completely resolved in that time frame. A 50% reduction in three dogs with lung tumors was observed after one month of treatment; two of the dogs who received continued zeolite lived for one year. Two of three dogs with bone cancer lived for a year and a half with continued treatment.


HUMAN CANCER CASE RESULTS

The results of specific human cancer cases treated with zeolite was among the most interesting and encouraging results obtained.

Four male patients with various cancers (liver, prostate, lung and intestinal) all showed significant improvement after taking Megamin (a zeolite supplement) in capsule form.

In Croatia, five critically ill cancer patients demonstrated significant improvement in their symptoms and condition after taking large doses (10 to 20 grams or more a day) of Megamin.

In 1998 and 1999 in Croatia, 114 cancer patients were followed with the Megamin treatment protocol. Terminal brain cancer patients showed some improvement in their condition within 3 to 4 weeks. Almost all of forty lung cancer patients showed decreased pain and improved respiration within the same time frame. Fifty-three Patients with terminal gastrointestinal cancers improved at a much slower rate.

Several other small groups of cancer patients in Austria or Croatia were treated with Megamin therapy and their results documented. In many cases p to 16 grams of micronized zeolite was given to the cancer patients in combinations of capsules and powder. Many of the patients chose to take the Megamin as their only therapy, refusing surgery, chemotherapy and radiation.

One of the patients with cancer of the larynx, taking the high amounts of Megamin listed above, experienced a decrease in the diameter of their tumor from 10 mm to 3 mm within nine months. The tumor also stabilized and became inactive.

A group of 16 cancer patients were treated by doctors at the Svecnjak Polyclinic with only Megamin therapy for a period of three years. At the end of the three years, 13 (81%) of the patients were in complete remission. This patient group included: 3 liver cancers, 4 metastatic melanoma, 2 bronchial carcinoma, 1 bladder cancer, and 1 hepatocellular carcinoma. The other 3 patients had obtained partial remission and stabilization of their cancers (2 lung cancer and 1 breast cancer).

In a second group of 16 cancer patients that added Megamin onto their traditional treatment with surgery, chemotherapy and radiation, half of the group, 8 patients, experienced complete remission. The other 8 patients experienced partial remission and disease stabilization.

Natural Cellular Zeolite Testimonials
(http://www.zeolitesupport.com/cellular-zeolite/catalog/Testimonials-sp-1.html)

Anecdotal information from doctors and patients. Click Here.

SOURCES

http://www.drzeolitedetox.com/orders.html

http://rawguru.com/store/raw-food/natural-cellular-zeolite-defense.html

http://zeolitebodydetox.com/orders.html

http://www.squidoo.com/naturalcellulardefenseliquidzeolite/

Amazon.com:
http://amazon.com/s/ref=nb_ss_gw/103-7536575-2318217?url=search-alias%3Daps&field-keywords=zeolite

http://www.toxinfreelifestyle.com/natural-cellular-defense.html

http://www.zeolitedepot.com/

Google: search term --- <zeolite> or <megamin>


What does the above information mean to the cancer patient? It means that there is one more safe, new, powerful therapeutic tool available to be combined with a non-toxic, non-invasive home-treatment protocol.

What it DOESN'T mean, according to integrative physicians, is that micronized zeolite is a panacea or cure for cancer. It is not. No miraculous monotherapy will ever cure cancer. However, zeolite might assist in reversing the condition, even eliminating it, in conjunction with other immunological and nutritional measures.



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