PubMed Citations on
Ellagic Acid - cancer
1: Han DH, Lee MJ, Kim JH. Related Articles, Links
Abstract Antioxidant and apoptosis-inducing activities of ellagic acid.
Anticancer Res. 2006 Sep-Oct;26(5A):3601-6.
PMID: 17094489 [PubMed - indexed for MEDLINE]
2: Hayeshi R, Mutingwende I, Mavengere W, Masiyanise V, Mukanganyama S. Related Articles, Links
Abstract The inhibition of human glutathione S-transferases activity by plant polyphenolic compounds ellagic acid and curcumin.
Food Chem Toxicol. 2007 Feb;45(2):286-95. Epub 2006 Aug 30.
PMID: 17046132 [PubMed - indexed for MEDLINE]
3: Whitley AC, Sweet DH, Walle T. Related Articles, Links
Abstract Site-specific accumulation of the cancer preventive dietary polyphenol ellagic acid in epithelial cells of the aerodigestive tract.
J Pharm Pharmacol. 2006 Sep;58(9):1201-9.
PMID: 16945178 [PubMed - indexed for MEDLINE]
4: Mertens-Talcott SU, Lee JH, Percival SS, Talcott ST. Related Articles, Links
Abstract Induction of cell death in Caco-2 human colon carcinoma cells by ellagic acid rich fractions from muscadine grapes (Vitis rotundifolia).
J Agric Food Chem. 2006 Jul 26;54(15):5336-43.
PMID: 16848514 [PubMed - indexed for MEDLINE]
5: Paivarinta E, Pajari AM, Torronen R, Mutanen M. Related Articles, Links
Abstract Ellagic acid and natural sources of ellagitannins as possible chemopreventive agents against intestinal tumorigenesis in the Min mouse.
Nutr Cancer. 2006;54(1):79-83.
PMID: 16800775 [PubMed - indexed for MEDLINE]
6: Stoner GD, Chen T, Kresty LA, Aziz RM, Reinemann T, Nines R. Related Articles, Links
Abstract Protection against esophageal cancer in rodents with lyophilized berries: potential mechanisms.
Nutr Cancer. 2006;54(1):33-46.
PMID: 16800771 [PubMed - indexed for MEDLINE]
7: Ratnam DV, Ankola DD, Bhardwaj V, Sahana DK, Kumar MN. Related Articles, Links
Abstract Role of antioxidants in prophylaxis and therapy: A pharmaceutical perspective.
J Control Release. 2006 Jul 20;113(3):189-207. Epub 2006 May 13. Review.
PMID: 16790290 [PubMed - in process]
8: Aggarwal BB, Shishodia S. Related Articles, Links
Abstract Molecular targets of dietary agents for prevention and therapy of cancer.
Biochem Pharmacol. 2006 May 14;71(10):1397-421. Epub 2006 Feb 23. Review.
PMID: 16563357 [PubMed - indexed for MEDLINE]
9: Larrosa M, Gonzalez-Sarrias A, Garcia-Conesa MT, Tomas-Barberan FA, Espin JC. Related Articles, Links
Abstract Urolithins, ellagic acid-derived metabolites produced by human colonic microflora, exhibit estrogenic and antiestrogenic activities.
J Agric Food Chem. 2006 Mar 8;54(5):1611-20.
PMID: 16506809 [PubMed - indexed for MEDLINE]
10: Adams LS, Seeram NP, Aggarwal BB, Takada Y, Sand D, Heber D. Related Articles, Links
Abstract Pomegranate juice, total pomegranate ellagitannins, and punicalagin suppress inflammatory cell signaling in colon cancer cells.
J Agric Food Chem. 2006 Feb 8;54(3):980-5.
PMID: 16448212 [PubMed - indexed for MEDLINE]
11: Larrosa M, Tomas-Barberan FA, Espin JC. Related Articles, Links
Abstract The dietary hydrolysable tannin punicalagin releases ellagic acid that induces apoptosis in human colon adenocarcinoma Caco-2 cells by using the mitochondrial pathway.
J Nutr Biochem. 2006 Sep;17(9):611-25. Epub 2005 Oct 11.
PMID: 16426830 [PubMed - indexed for MEDLINE]
12: Barta I, Smerak P, Polivkova Z, Sestakova H, Langova M, Turek B, Bartova J. Related Articles, Links
Abstract Current trends and perspectives in nutrition and cancer prevention.
Neoplasma. 2006;53(1):19-25.
PMID: 16416008 [PubMed - indexed for MEDLINE]
13: Papoutsi Z, Kassi E, Tsiapara A, Fokialakis N, Chrousos GP, Moutsatsou P. Related Articles, Links
Abstract Evaluation of estrogenic/antiestrogenic activity of ellagic acid via the estrogen receptor subtypes ERalpha and ERbeta.
J Agric Food Chem. 2005 Oct 5;53(20):7715-20.
PMID: 16190622 [PubMed - indexed for MEDLINE]
14: Seeram NP, Adams LS, Henning SM, Niu Y, Zhang Y, Nair MG, Heber D. Related Articles, Links
Abstract In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagic acid and a total pomegranate tannin extract are enhanced in combination with other polyphenols as found in pomegranate juice.
J Nutr Biochem. 2005 Jun;16(6):360-7.
PMID: 15936648 [PubMed - indexed for MEDLINE]
15: Bhosle SM, Huilgol NG, Mishra KP. Related Articles, Links
Abstract Enhancement of radiation-induced oxidative stress and cytotoxicity in tumor cells by ellagic acid.
Clin Chim Acta. 2005 Sep;359(1-2):89-100.
PMID: 15922998 [PubMed - indexed for MEDLINE]
16: Whitley AC, Sweet DH, Walle T. Related Articles, Links
Free Full Text The dietary polyphenol ellagic acid is a potent inhibitor of hOAT1.
Drug Metab Dispos. 2005 Aug;33(8):1097-100. Epub 2005 May 3.
PMID: 15870380 [PubMed - indexed for MEDLINE]
17: Li TM, Chen GW, Su CC, Lin JG, Yeh CC, Cheng KC, Chung JG. Related Articles, Links
Abstract Ellagic acid induced p53/p21 expression, G1 arrest and apoptosis in human bladder cancer T24 cells.
Anticancer Res. 2005 Mar-Apr;25(2A):971-9.
PMID: 15868936 [PubMed - indexed for MEDLINE]
18: Han C, Ding H, Casto B, Stoner GD, D'Ambrosio SM. Related Articles, Links
Abstract Inhibition of the growth of premalignant and malignant human oral cell lines by extracts and components of black raspberries.
Nutr Cancer. 2005;51(2):207-17.
PMID: 15860443 [PubMed - indexed for MEDLINE]
19: Ray A. Related Articles, Links
Abstract Cancer preventive role of selected dietary factors.
Indian J Cancer. 2005 Jan-Mar;42(1):15-24. Review.
PMID: 15805687 [PubMed - indexed for MEDLINE]
20: Elmore E, Siddiqui S, Navidi M, Steele VE, Redpath JL. Related Articles, Links
Abstract Correlation of in vitro chemopreventive efficacy data from the human epidermal cell assay with animal efficacy data and clinical trial plasma levels.
J Cell Biochem. 2005 Jun 1;95(3):571-88.
PMID: 15786488 [PubMed - indexed for MEDLINE]
21: Falsaperla M, Morgia G, Tartarone A, Ardito R, Romano G. Related Articles, Links
Abstract Support ellagic acid therapy in patients with hormone refractory prostate cancer (HRPC) on standard chemotherapy using vinorelbine and estramustine phosphate.
Eur Urol. 2005 Apr;47(4):449-54; discussion 454-5. Epub 2005 Jan 19.
PMID: 15774240 [PubMed - indexed for MEDLINE]
22: Lansky EP, Harrison G, Froom P, Jiang WG. Related Articles, Links
Abstract Pomegranate (Punica granatum) pure chemicals show possible synergistic inhibition of human PC-3 prostate cancer cell invasion across Matrigel.
Invest New Drugs. 2005 Mar;23(2):121-2. Erratum in: Invest New Drugs. 2005 Aug;23(4):379.
PMID: 15744587 [PubMed - indexed for MEDLINE]
23: Rangkadilok N, Worasuttayangkurn L, Bennett RN, Satayavivad J. Related Articles, Links
Abstract Identification and quantification of polyphenolic compounds in Longan (Euphoria longana Lam.) fruit.
J Agric Food Chem. 2005 Mar 9;53(5):1387-92.
PMID: 15740011 [PubMed - indexed for MEDLINE]
24: Mertens-Talcott SU, Bomser JA, Romero C, Talcott ST, Percival SS. Related Articles, Links
Free Full Text Ellagic acid potentiates the effect of quercetin on p21waf1/cip1, p53, and MAP-kinases without affecting intracellular generation of reactive oxygen species in vitro.
J Nutr. 2005 Mar;135(3):609-14.
PMID: 15735102 [PubMed - indexed for MEDLINE]
25: Mertens-Talcott SU, Percival SS. Related Articles, Links
Abstract Ellagic acid and quercetin interact synergistically with resveratrol in the induction of apoptosis and cause transient cell cycle arrest in human leukemia cells.
Cancer Lett. 2005 Feb 10;218(2):141-51.
PMID: 15670891 [PubMed - in process]
26: Labrecque L, Lamy S, Chapus A, Mihoubi S, Durocher Y, Cass B, Bojanowski MW, Gingras D, Beliveau R. Related Articles, Links
Free Full Text Combined inhibition of PDGF and VEGF receptors by ellagic acid, a dietary-derived phenolic compound.
Carcinogenesis. 2005 Apr;26(4):821-6. Epub 2005 Jan 20.
PMID: 15661805 [PubMed - indexed for MEDLINE]
27: Aggarwal BB, Shishodia S. Related Articles, Links
Abstract Suppression of the nuclear factor-kappaB activation pathway by spice-derived phytochemicals: reasoning for seasoning.
Ann N Y Acad Sci. 2004 Dec;1030:434-41. Review.
PMID: 15659827 [PubMed - indexed for MEDLINE]
28: Cerda B, Tomas-Barberan FA, Espin JC. Related Articles, Links
Abstract Metabolism of antioxidant and chemopreventive ellagitannins from strawberries, raspberries, walnuts, and oak-aged wine in humans: identification of biomarkers and individual variability.
J Agric Food Chem. 2005 Jan 26;53(2):227-35.
PMID: 15656654 [PubMed - indexed for MEDLINE]
29: de Boer JG, Yang H, Holcroft J, Skov K. Related Articles, Links
Abstract Chemoprotection against N-nitrosomethylbenzylamine-induced mutation in the rat esophagus.
Nutr Cancer. 2004;50(2):168-73.
PMID: 15623463 [PubMed - indexed for MEDLINE]
30: Losso JN, Bansode RR, Trappey A 2nd, Bawadi HA, Truax R. Related Articles, Links
Abstract In vitro anti-proliferative activities of ellagic acid.
J Nutr Biochem. 2004 Nov;15(11):672-8.
PMID: 15590271 [PubMed - indexed for MEDLINE]
31: Afaq F, Malik A, Syed D, Maes D, Matsui MS, Mukhtar H. Related Articles, Links
Abstract Pomegranate fruit extract modulates UV-B-mediated phosphorylation of mitogen-activated protein kinases and activation of nuclear factor kappa B in normal human epidermal keratinocytes paragraph sign.
Photochem Photobiol. 2005 Jan-Feb;81(1):38-45.
PMID: 15493960 [PubMed - indexed for MEDLINE]
32: Dorai T, Aggarwal BB. Related Articles, Links
Abstract Role of chemopreventive agents in cancer therapy.
Cancer Lett. 2004 Nov 25;215(2):129-40. Review.
PMID: 15488631 [PubMed - indexed for MEDLINE]
33: Aggarwal BB, Takada Y, Oommen OV. Related Articles, Links
Abstract From chemoprevention to chemotherapy: common targets and common goals.
Expert Opin Investig Drugs. 2004 Oct;13(10):1327-38. Review.
PMID: 15461561 [PubMed - indexed for MEDLINE]
34: Maciel ME, Castro GD, Castro JA. Related Articles, Links
Abstract Inhibition of the rat breast cytosolic bioactivation of ethanol to acetaldehyde by some plant polyphenols and folic acid.
Nutr Cancer. 2004;49(1):94-9.
PMID: 15456641 [PubMed - indexed for MEDLINE]
35: Pillai SP, Mitscher LA, Menon SR, Pillai CA, Shankel DM. Related Articles, Links
Abstract Antimutagenic/antioxidant activity of green tea components and related compounds.
J Environ Pathol Toxicol Oncol. 1999;18(3):147-58.
PMID: 15281227 [PubMed - indexed for MEDLINE]
36: Hannum SM. Related Articles, Links
Abstract Potential impact of strawberries on human health: a review of the science.
Crit Rev Food Sci Nutr. 2004;44(1):1-17. Review.
PMID: 15077879 [PubMed - indexed for MEDLINE]
37: Whitley AC, Stoner GD, Darby MV, Walle T. Related Articles, Links
Abstract Intestinal epithelial cell accumulation of the cancer preventive polyphenol ellagic acid--extensive binding to protein and DNA.
Biochem Pharmacol. 2003 Sep 15;66(6):907-15.
PMID: 12963477 [PubMed - indexed for MEDLINE]
38: Mertens-Talcott SU, Talcott ST, Percival SS. Related Articles, Links
Free Full Text Low concentrations of quercetin and ellagic acid synergistically influence proliferation, cytotoxicity and apoptosis in MOLT-4 human leukemia cells.
J Nutr. 2003 Aug;133(8):2669-74.
PMID: 12888656 [PubMed - indexed for MEDLINE]
39: van der Logt EM, Roelofs HM, Nagengast FM, Peters WH. Related Articles, Links
Free Full Text Induction of rat hepatic and intestinal UDP-glucuronosyltransferases by naturally occurring dietary anticarcinogens.
Carcinogenesis. 2003 Oct;24(10):1651-6. Epub 2003 Jul 17.
PMID: 12869420 [PubMed - indexed for MEDLINE]
Asami Y, Ogura T, Otake N, Nishimura T, Xinsheng Y, Sakurai T, Nagasawa H, Sakuda S, Tatsuta K. Related Articles, Links
Isolation and synthesis of a new bioactive ellagic acid derivative from Combretum yunnanensis.
J Nat Prod. 2003 May;66(5):729-31.
PMID: 12762821 [PubMed - indexed for MEDLINE]

41: Gerhauser C, Klimo K, Heiss E, Neumann I, Gamal-Eldeen A, Knauft J, Liu GY, Sitthimonchai S, Frank N. Related Articles, Links
Abstract Mechanism-based in vitro screening of potential cancer chemopreventive agents.
Mutat Res. 2003 Feb-Mar;523-524:163-72.
PMID: 12628514 [PubMed - indexed for MEDLINE]
42: Gopalakrishna R, Gundimeda U. Related Articles, Links
Free Full Text Antioxidant regulation of protein kinase C in cancer prevention.
J Nutr. 2002 Dec;132(12):3819S-3823S.
PMID: 12468631 [PubMed - indexed for MEDLINE]
43: Saleem A, Husheem M, Harkonen P, Pihlaja K. Related Articles, Links
Abstract Inhibition of cancer cell growth by crude extract and the phenolics of Terminalia chebula retz. fruit.
J Ethnopharmacol. 2002 Aug;81(3):327-36.
PMID: 12127233 [PubMed - indexed for MEDLINE]
44: Narayanan BA, Narayanan NK, Stoner GD, Bullock BP. Related Articles, Links
Abstract Interactive gene expression pattern in prostate cancer cells exposed to phenolic antioxidants.
Life Sci. 2002 Mar 1;70(15):1821-39.
PMID: 12002526 [PubMed - indexed for MEDLINE]
45: Harris GK, Gupta A, Nines RG, Kresty LA, Habib SG, Frankel WL, LaPerle K, Gallaher DD, Schwartz SJ, Stoner GD. Related Articles, Links
Abstract Effects of lyophilized black raspberries on azoxymethane-induced colon cancer and 8-hydroxy-2'-deoxyguanosine levels in the Fischer 344 rat.
Nutr Cancer. 2001;40(2):125-33.
PMID: 11962247 [PubMed - indexed for MEDLINE]
46: Hirose M, Nishikawa A, Shibutani M, Imai T, Shirai T. Related Articles, Links
Abstract Chemoprevention of heterocyclic amine-induced mammary carcinogenesis in rats.
Environ Mol Mutagen. 2002;39(2-3):271-8.
PMID: 11921198 [PubMed - indexed for MEDLINE]
47: Festa F, Aglitti T, Duranti G, Ricordy R, Perticone P, Cozzi R. Related Articles, Links
Abstract Strong antioxidant activity of ellagic acid in mammalian cells in vitro revealed by the comet assay.
Anticancer Res. 2001 Nov-Dec;21(6A):3903-8.
PMID: 11911267 [PubMed - indexed for MEDLINE]
48: Lin SS, Hung CF, Tyan YS, Yang CC, Hsia TC, Yang MD, Chung JG. Related Articles, Links
Abstract Ellagic [correction of ellagica] acid inhibits arylamine N-acetyltransferase activity and DNA adduct formation in human bladder tumor cell lines (T24 and TSGH 8301).
Urol Res. 2001 Dec;29(6):371-6.
PMID: 11828989 [PubMed - indexed for MEDLINE]
49: Malmquist NA, Anzinger JJ, Hirzel D, Buxton IL. Related Articles, Links
No abstract Ellagic acid inhibits nucleoside diphosphate kinase-B activity.
Proc West Pharmacol Soc. 2001;44:57-9. No abstract available.
PMID: 11793995 [PubMed - indexed for MEDLINE]
50: Kinjo J, Nagao S, Tanaka T, Nonaka GI, Okabe H. Related Articles, Links
Free Full Text Antiproliferative constituents in the plant 8. Seeds of Rhynchosia volubilis.
Biol Pharm Bull. 2001 Dec;24(12):1443-5.
PMID: 11767121 [PubMed - indexed for MEDLINE]
51: Kresty LA, Morse MA, Morgan C, Carlton PS, Lu J, Gupta A, Blackwood M, Stoner GD. Related Articles, Links
Free Full Text Chemoprevention of esophageal tumorigenesis by dietary administration of lyophilized black raspberries.
Cancer Res. 2001 Aug 15;61(16):6112-9.
PMID: 11507061 [PubMed - indexed for MEDLINE]
52: Smith WA, Freeman JW, Gupta RC. Related Articles, Links
Abstract Effect of chemopreventive agents on DNA adduction induced by the potent mammary carcinogen dibenzo[a,l]pyrene in the human breast cells MCF-7.
Mutat Res. 2001 Sep 1;480-481:97-108.
PMID: 11506803 [PubMed - indexed for MEDLINE]
53: Perchellet EM, Sperfslage BJ, Qabaja G, Jones GB, Perchellet JP. Related Articles, Links
Abstract Quinone isomers of the WS-5995 antibiotics: synthetic antitumor agents that inhibit macromolecule synthesis, block nucleoside transport, induce DNA fragmentation, and decrease the growth and viability of L1210 leukemic cells more effectively than ellagic acid and genistein in vitro.
Anticancer Drugs. 2001 Jun;12(5):401-17.
PMID: 11395569 [PubMed - indexed for MEDLINE]
54: Narayanan BA, Re GG. Related Articles, Links
Abstract IGF-II down regulation associated cell cycle arrest in colon cancer cells exposed to phenolic antioxidant ellagic acid.
Anticancer Res. 2001 Jan-Feb;21(1A):359-64.
PMID: 11299762 [PubMed - indexed for MEDLINE]
55: Xue H, Aziz RM, Sun N, Cassady JM, Kamendulis LM, Xu Y, Stoner GD, Klaunig JE. Related Articles, Links
Free Full Text Inhibition of cellular transformation by berry extracts.
Carcinogenesis. 2001 Feb;22(2):351-6. Erratum in: Carcinogenesis 2001 May;22(5):831-3.
PMID: 11181460 [PubMed - indexed for MEDLINE]
56: Lin SS, Hung CF, Ho CC, Liu YH, Ho HC, Chung JG. Related Articles, Links
Abstract Effects of ellagic acid by oral administration on N-acetylation and metabolism of 2-aminofluorene in rat brain tissues.
Neurochem Res. 2000 Nov;25(11):1503-8.
PMID: 11071370 [PubMed - indexed for MEDLINE]
57: Shepherd AG, Manson MM, Ball HW, McLellan LI. Related Articles, Links
Free Full Text Regulation of rat glutamate-cysteine ligase (gamma-glutamylcysteine synthetase) subunits by chemopreventive agents and in aflatoxin B(1)-induced preneoplasia.
Carcinogenesis. 2000 Oct;21(10):1827-34.
PMID: 11023540 [PubMed - indexed for MEDLINE]
58: Stoner GD, Kresty LA, Carlton PS, Siglin JC, Morse MA. Related Articles, Links
Free Full Text Isothiocyanates and freeze-dried strawberries as inhibitors of esophageal cancer.
Toxicol Sci. 1999 Dec;52(2 Suppl):95-100.
PMID: 10630596 [PubMed - indexed for MEDLINE]
59: Nepka C, Asprodini E, Kouretas D. Related Articles, Links
Abstract Tannins, xenobiotic metabolism and cancer chemoprevention in experimental animals.
Eur J Drug Metab Pharmacokinet. 1999 Apr-Jun;24(2):183-9. Review.
PMID: 10510748 [PubMed - indexed for MEDLINE]
60: Khanduja KL, Gandhi RK, Pathania V, Syal N. Related Articles, Links
Abstract Prevention of N-nitrosodiethylamine-induced lung tumorigenesis by ellagic acid and quercetin in mice.
Food Chem Toxicol. 1999 Apr;37(4):313-8.
PMID: 10418948 [PubMed - indexed for MEDLINE]